| Autor: |
Maryam Haghighi, Sajad Moradi, Amin Nowroozi, Meisam Tahmasbi, Mohamad javad Naseri, Kasra Karami, Mohsen Shahlaei |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of biomolecular structuredynamics. |
| ISSN: |
1538-0254 |
| Popis: |
In this study, the interaction of an anticonvulsant drug that used in the treatment of epilepsy, Lamotrigine (LTG) with the most important transport protein of the blood, human serum albumin (HSA) has been studied by using the electrochemical methods and molecular modeling techniques. For this purpose, a simple carbon paste electrode (CPE) was applied for electrocatalytic oxidation and investigation of LTG interaction with HSA. The stoichiometry of the complex between LTG and HSA and the binding constant (K |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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