Phosphoglycerate mutase has essential arginyl residues
| Autor: | Brett A. Wilson, C.L. Borders |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
2
3-Diphosphoglycerate Phosphoglycerate Mutase Glyceric acid biology Arginine Protein subunit Coenzymes Biophysics Cell Biology Glyceric Acids Biochemistry Catalysis Cofactor Enzyme Activation Phosphoglycerate mutase chemistry.chemical_compound Residue (chemistry) Enzyme activator chemistry Reagent biology.protein Epoxy Compounds Molecular Biology |
| Zdroj: | Biochemical and Biophysical Research Communications. 73:978-984 |
| ISSN: | 0006-291X |
| DOI: | 10.1016/0006-291x(76)90218-7 |
| Popis: | Phosphoglycerate mutase is inactivated by butanedione in borate buffer. Inactivation by 0.13 mM reagent correlates with the modification of one arginyl residue per subunit, and is prevented by either 2, 3-diphosphoglycerate or 3-phosphoglycerate. With 0.50 mM butanedione, inactivation is accompanied by the modification of three arginyl residues per subunit, two of which are protected by the combined presence of cofactor and substrate. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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