Mechanistic implication of decreased plasma atrial natriuretic peptide level for transient rise in the atrial capture threshold early after ICD or CRT-D implantation

Autor: Akira Kimata, Noriyuki Takeyasu, Yuichi Noguchi, Hidetaka Nishina, Kojiro Ogawa, Masaki Ieda, Akihiko Nogami, Yoshiko Uehara, Mari Ebine, Kazutaka Aonuma, Kentaro Yoshida
Rok vydání: 2018
Předmět:
Male
medicine.medical_specialty
medicine.drug_class
medicine.medical_treatment
Cardiac resynchronization therapy
030204 cardiovascular system & hematology
Risk Assessment
Sensitivity and Specificity
Statistics
Nonparametric
Sick sinus syndrome
Cardiac Resynchronization Therapy
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Atrial natriuretic peptide
Physiology (medical)
Internal medicine
medicine
Natriuretic peptide
Humans
Prospective Studies
030212 general & internal medicine
Aged
Heart Failure
Sick Sinus Syndrome
Analysis of Variance
Ejection fraction
business.industry
Middle Aged
Prognosis
medicine.disease
Brain natriuretic peptide
Implantable cardioverter-defibrillator
Survival Analysis
Defibrillators
Implantable
Heart failure
cardiovascular system
Cardiology
Female
Cardiology and Cardiovascular Medicine
business
Atrial Natriuretic Factor
Biomarkers
Zdroj: Journal of Interventional Cardiac Electrophysiology. 53:131-140
ISSN: 1572-8595
1383-875X
DOI: 10.1007/s10840-018-0409-0
Popis: Despite the use of steroid-eluting leads, a transient but not persistent rise in the atrial/ventricular capture threshold (TRACT/TRVCT) can occur early after pacemaker implantation in patients with sick sinus syndrome. This study aimed to assess the prevalence, predictors, and mechanisms of TRACT/TRVCT in patients with heart failure undergoing implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy (CRT) implantation. One hundred twenty consecutive patients underwent ICD (N = 70) or CRT (N = 50) implantation. Capture threshold was measured at implantation, 7-day, 1-month, and 6-month post-implantation. TRACT/TRVCT was defined as a threshold rise at 7 days by more than twice the height of the threshold at implantation, with full recovery during follow-up. Atrial and brain natriuretic peptide (ANP and BNP) levels were measured before implantation. TRACT and TRVCT were observed in 13 (11%) and 10 (8%) patients, respectively. Patients with TRACT had lower ANP level (median 72 [42–105] vs. 99 [49–198] pg/mL, P = 0.06), lower ANP/BNP ratio (0.29 [0.20–0.36] vs. 0.50 [0.33–0.70], P
Databáze: OpenAIRE
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