Feasibility of ultrashort echo time (UTE) T2* cartilage mapping in the hip: a pilot study
| Autor: | Patrick Quarterman, Michael J. Rasiej, Diego Jaramillo, Sachin Jambawalikar, Thomas Sean Lynch, Tony T Wong |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Cartilage
Articular 030222 orthopedics Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Echo time Cartilage Reproducibility of Results Magnetic resonance imaging Pilot Projects General Medicine Magnetic Resonance Imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure medicine Feasibility Studies Humans Radiology Nuclear Medicine and imaging Ultrashort echo time Femur business Biomedical engineering |
| Zdroj: | Acta radiologica (Stockholm, Sweden : 1987). 63(6) |
| ISSN: | 1600-0455 |
| Popis: | Background Ultrashort echo time (UTE) T2* is sensitive to molecular changes within the deep calcified layer of cartilage. Feasibility of its use in the hip needs to be established to determine suitability for clinical use. Purpose To establish feasibility of UTE T2* cartilage mapping in the hip and determine if differences in regional values exist. Material and Methods MRI scans with UTE T2* cartilage maps were prospectively acquired on eight hips. Hip cartilage was segmented into whole and deep layers in anterosuperior, superior, and posterosuperior regions. Quantitative UTE T2* maps were analyzed (independent one-way ANOVA) and reliability was calculated (ICC). Results UTE T2* mean values (anterosuperior, superior, posterosuperior): full femoral layer (19.55, 18.43, 16.84 ms) ( P=0.004), full acetabular layer (19.37, 17.50, 16.73 ms) ( P=0.013), deep femoral layer (18.68, 17.90, 15.74 ms) ( P=0.010), and deep acetabular layer (17.81, 16.18, 15.31 ms) ( P=0.007). Values were higher in anterosuperior compared to posterosuperior regions (mean difference; 95% confidence interval [CI]): full femur layer (2.71 ms; 95% CI 0.91–4.51: P=0.003), deep femur layer (2.94 ms; 95% CI 0.69–5.19; P=0.009), full acetabular layer (2.63 ms 95% CI 0.55–4.72; P=0.012), and deep acetabular layer (2.50 ms; 95% CI 0.69–4.30; P=0.006). Intra-reader (ICC 0.89–0.99) and inter-reader reliability (ICC 0.63–0.96) were good to excellent for the majority of cartilage layers. Conclusion UTE T2* cartilage mapping was feasible in the hip with mean values in the range of 16.84–19.55 ms in the femur and 16.73–19.37 ms in the acetabulum. Significantly higher values were present in the anterosuperior region compared to the posterosuperior region. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|