| Autor: |
Abhishek Poddar, Yen-Yu Hsu, Faith Zhang, Abeda Shamma, Zachary Kreais, Clare Muller, Mamata Malla, Aniruddha Ray, Allen P. Liu, Qian Chen |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Molecular biology of the cell. 33(14) |
| ISSN: |
1939-4586 |
| Popis: |
Pkd2 is the fission yeast homologue of polycystins. This putative ion channel localizes to the plasma membrane. It is required for the expansion of cell volume during interphase growth and cytokinesis, the last step of cell division. However, the channel activity of Pkd2 remains untested. Here, we examined the calcium permeability and mechanosensitivity of Pkd2 through in vitro reconstitution and calcium imaging of |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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