Protein expression pattern of tissue inhibitor of metalloproteinase-3 (TIMP3) in endometriosis and normal endometrium

Autor:	Dimosthenis Miliaras, Anna Timologou, Basil C. Tarlatzis, Menelaos Zafrakas, Grigorios Grimbizis, Konstantinos Kotronis, Panayiota Papasozomenou
Rok vydání:	2019
Předmět:	Adult Endocrinology Diabetes and Metabolism Endometriosis 030209 endocrinology & metabolism Matrix metalloproteinase Protein expression Extracellular matrix Endometrium 03 medical and health sciences 0302 clinical medicine Endocrinology medicine Humans Ovarian Diseases Prospective Studies Eutopic endometrium Tissue Inhibitor of Metalloproteinase-3 030219 obstetrics & reproductive medicine Chemistry Obstetrics and Gynecology Tissue inhibitor of metalloproteinase Normal endometrium medicine.disease Immunohistochemistry Case-Control Studies Cancer research Female Laparoscopy
Zdroj:	Gynecological Endocrinology. 35:1103-1106
ISSN:	1473-0766 0951-3590
DOI:	10.1080/09513590.2019.1625880
Popis:	Given the involvement of different extracellular matrix (ECM) metalloproteinases (MMPs) in endometriosis, the protein expression pattern of tissue inhibitor of metalloproteinase-3 (TIMP3) was analyzed in this study in endometriosis and normal endometrium. Tissue samples were collected prospectively from 64 premenopausal patients undergoing operative laparoscopy. Protein expression of TIMP3 was analyzed immunohistochemically in endometriotic lesions (
Databáze:	OpenAIRE
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