HIRSUTISM; ETIOLOGICAL PROFILE IN ABBOTTABAD, PAKISTAN
| Autor: | Muhammad Usman Anjum, Hashim Riaz, Surriya Yasmin, Syed Humayun Shah |
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| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | THE PROFESSIONAL MEDICAL JOURNAL. 23:741-745 |
| ISSN: | 2071-7733 1024-8919 |
| DOI: | 10.17957/tpmj/16.3382 |
| Popis: | elf-esteem, psychological distress and cosmetic embarrassment. Objective: Tostudy the clinical, biochemical and etiological profile of patients with hirsutism in Abbottabad,Pakistan. Duration and place: This descriptive study was performed in Frontier Medical & DentalCollege, Abbottabad from January, 2015 to December, 2015. Methods: Fifty patients wereincluded in the study. Complete clinical assessment and abdominal and pelvic ultrasonographywas carried out. Ferriman and Gallwey score was used to assess the extent and pattern ofhirsutism. Endocrinological investigations performed in these patients included prolactin,testosterone, luteinizing and follicular stimulating hormone (LH, FSH), thyroid function testsand cortisol. Results: Fifty patients were included in the study. Their mean age was 28.30±5.83years. About 88% of the women were married and 70% were obese. The polycystic ovariansyndrome (58%) was diagnosed as the main cause of hirsutism followed by idiopathic hirsutism(38%) and drug-induced hirsutism (4%). Majority of patients, 50%, had hirsutism for 1-5 yearswhile 22% and 20% had hirsutism for 6-10 years and > 10 years respectively. The rate of infertilityamong hirsute women was 70% (35 cases), out of which, 24 (48%) cases had primary infertilitywhile 11 (22%) had secondary infertility. Most of the hirsuite patients, 26 (52%), presented withthe complaints of infertility and menstrual disturbances followed by infertility alone in 9 (18%)cases, hirsutism in 6 (12%) cases and menstrual irregularities in 5 (10%). The 60% of patientsbelonged to moderate category according to FG score, (FG score 17-24). The 26% belonged tomild category (FG score 8-16) and 14% belonged to severe category (FG score 25-30). About72% of our patients used treatment of any kind for their disease. The common hair removingpractices used by these patients included bleaching (22%), waxing (20%), epilation (20%),electrolysis (6%) and shaving (4%). Serum free testosterone levels were elevated in 44% of ourpatients, LH/FSH ratio was more than 2 in 42.1% patients and prolactin levels were raised in10% of the patients. Conclusion: Hirsutism is not uncommon in Pakistan. The most commoncause of hirsutism was polycystic ovarian syndrome and idiopathic hirsutism. There is a need toconduct large scale studies to determine the true prevalence and etiological profile of patientswith hirsutism. |
| Databáze: | OpenAIRE |
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