Studies on the periodicity and intravascular distribution of Wuchereria bancrofti microfilariae in paired samples of capillary and venous blood from Recife, Brazil
| Autor: | Amaury Coutinho, Izolda Moura, Gerusa Dreyer, Fátima Béliz, Luiz Augustinho M Da Silva, Zulma Medeiros, Abraham Rocha, Agueda Pimentael, Luiz Dias de Andrade, Willy F. Piessens |
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| Rok vydání: | 1996 |
| Předmět: |
Periodicity
Time Factors Capillary action Physiology Biology medicine.disease_cause Microfilaria Sensitivity and Specificity Filariasis Veins Paired samples parasitic diseases medicine Distribution (pharmacology) Animals Humans Wuchereria bancrofti Microfilariae Blood Specimen Collection Public Health Environmental and Occupational Health Reproducibility of Results Venous blood Feeding Behavior medicine.disease Capillaries Insect Vectors Culex Infectious Diseases Lymphatic system Immunology Parasitology Brazil |
| Zdroj: | Tropical medicineinternational health : TMIH. 1(2) |
| ISSN: | 1360-2276 |
| Popis: | We examined the periodicity and intravascular distribution of Wuchereria bancrofti microfilariae (mf) and determined the effect of these parasite properties on the accuracy of blood filming and filtration methods for diagnosis of bancroftian filariasis in the endemic area of Recife, Brazil. Microfilariae in both venous and capillary blood exhibited a nocturnal periodicity pattern with a relatively high amplitude. Overall, capillary blood contained approximately 1.25 times the number of mf present at the same time in the same volume of venous blood. However, the ratio of mf present in capillary and venous blood varied over a 24-hour period, so that the fewest mf were present in the capillary bed of the skin at the time when biting activity of the local Culex vector is the lowest. Twenty or 60 microliters blood films did not reliably detect carriers with fewer than 100 or 60 mf/ml venous blood, respectively, and were thus inadequate for the identification of low density mf carriers. In contrast, all carriers with > 1 mf/20 or 60 microliters blood smear at night could be identified during daytime hours by filtration of 1 micromilligram venous blood. |
| Databáze: | OpenAIRE |
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