Selective staining of gastric biopsies for H. pylori does not affect detection rates or turnaround time and improves cost compared to reflexive staining
| Autor: | Joshua K. Routh, Lauren Decker, Joshua A. Hanson, Jessica Sara Snider |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Time Factors Biopsy 030204 cardiovascular system & hematology Affect (psychology) Gastroenterology Turnaround time Stain Sensitivity and Specificity Pathology and Forensic Medicine Helicobacter Infections 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans biology medicine.diagnostic_test Helicobacter pylori Staining and Labeling business.industry Stomach Selective staining Cell Biology biology.organism_classification Immunohistochemistry Surgery Staining 030220 oncology & carcinogenesis Cohort business |
| Zdroj: | Pathology, research and practice. 213(1) |
| ISSN: | 1618-0631 |
| Popis: | Aims To evaluate how reflexive versus selective H. pylori stains affect detection rates, turnaround time (TAT), and cost savings in a real life practice environment following an institutional policy change. Methods The aforementioned parameters were evaluated in all cases in the year preceding and the year following an institutional policy change from reflexive to selective staining. Results 1497 patients comprised the reflexive stain (RS) group of which 228 (15.2%) were H. pylori positive. 1629 patients comprised the selective stain (SS) group of which 237 (14.5%) were H. pylori positive. There was no significant difference in H. pylori detection rates between the RS and SS groups (OR = 0.95, 95% CI = 0.78–1.15, p = 0.59). TATs were similarly equivalent with a mean of 52.4 h for the RS cohort and 53.7 h for the SS cohort (p = 0.344), both of which included a resident preview day. We calculated an average laboratory cost savings of $11.68 per case, which saved our department over $15,000 (37%) in the year following the policy change. Conclusions Our results support a policy of selective staining for H. pylori as opposed to reflexive staining and go on to show that laboratories that change their policy can expect to generate cost savings without compromising detection rates or TAT. |
| Databáze: | OpenAIRE |
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