Stereoselective Synthesis of 2‐Oxyenamides**

Autor:	Sara‐Cathrin Krieg, Jennifer Grimmer, Annika Maria Pick, Harald Kelm, Martin Breugst, Georg Manolikakes
Rok vydání:	2022
Předmět:	Organic Chemistry Physical and Theoretical Chemistry
Zdroj:	European Journal of Organic Chemistry. 2022
ISSN:	1099-0690 1434-193X
Popis:	An improved route for the highly stereoselective synthesis of (Z)-2-oxyenamides is reported. The desired products can be accessed in only three steps from aminoacetaldehyde dimethyl acetal as common, readily available building block in a highly modular fashion. The improved procedure has been applied to the synthesis of various acylated and sufonylated oxyenamides. Mechanistic and theoretical studies provide a conclusive rationale for the observed stereoselectivities.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbec0831cd09d7de81fc14d81feeacf https://doi.org/10.1002/ejoc.202200772 Zobrazit plný text záznamu Plný text