Hypertrophic Cardiomyopathy: A Species-Spanning Pathology
| Autor: | Barbara N. Horowitz |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
business.industry
Range (biology) Hypertrophic cardiomyopathy 030204 cardiovascular system & hematology Cardiomyopathy Hypertrophic medicine.disease Bioinformatics Sudden death Natural history 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine 030202 anesthesiology Medicine Humans Young adult Cardiology and Cardiovascular Medicine Veterinary cardiology business |
| Zdroj: | Journal of cardiothoracic and vascular anesthesia. 35(9) |
| ISSN: | 1532-8422 |
| Popis: | Hypertrophic cardiomyopathy (HCM), a leading cause of sudden death among athletes and young adults is not uniquely human. 1 The disorder has been diagnosed in a wide range of other mammalian species and is seen with some frequency in certain domestic animals (Figure 1). 2-16 The clinical characteristics, natural history and therapeutic interventions are similar across species. Comparative genomic analyses point to overlapping genetic basis for the disorder in humans and other animals, in particular certain domestic cat breeds. 2 , 3 , 4 , 5 , 6 Increased knowledge exchange between the fields of human and veterinary cardiology can expand how HCM is understood, treated, and potentially prevented across the tree of life. |
| Databáze: | OpenAIRE |
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