Detection of unruptured intracranial aneurysms on noninvasive imaging. Is there still a role for digital subtraction angiography?
| Autor: | Fady T. Charbel, Sepideh Amin-Hanjani, Oriela Rustemi, Jennifer L Orning, Victor A. Aletich, Xinjian Du, Sophia F. Shakur, Ali Alaraj |
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| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.diagnostic_test business.industry Incidence (epidemiology) Angiography Retrospective cohort study Magnetic resonance imaging computed tomography Digital subtraction angiography medicine.disease digital subtraction angiography Magnetic resonance angiography Aneurysm cerebral aneurysm medicine magnetic resonance imaging Surgery Original Article Neurology (clinical) cardiovascular diseases business Nuclear medicine Computed tomography angiography |
| Zdroj: | Surgical Neurology International |
| ISSN: | 2229-5097 |
| Popis: | Background: To determine the utility of digital subtraction angiography (DSA) in patients with unruptured intracranial aneurysms (UIA) detected on noninvasive imaging, such as magnetic resonance angiography (MRA) and computed tomography angiography (CTA). The follow-up of patients with untreated UIAs involves serial imaging; however, this diagnosis may be based on false positive (FP) results. We examined the incidence of FPs in our institutional series. Methods: DSAs performed at our institution from January 2011 to June 2014 were retrospectively reviewed and patients referred with UIA detected on noninvasive imaging were selected. Clinical presentation as well as aneurysm location, size, and number reported on DSA and noninvasive imaging were assessed. Results: Two hundred and eighty six patients (mean age 56.8 years, female 74.8%) with a total of 355 UIA were included. Thirty-one patients had a symptomatic presentation. Analysis per patient showed the pooled FP rate of noninvasive imaging was 15%. MRA FP was 13% (22/171) and CTA FP was 18% (22/120). FP increased significantly with aneurysm size < 3.5 mm on MRA (P < 0.001) and |
| Databáze: | OpenAIRE |
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