Spontaneously ruptured hepatocellular carcinoma in Fontan-associated liver disease: A case report
| Autor: | Hideto Kawaratani, Yosuke Aihara, Ryuichi Noguchi, Takahiro Kubo, Tadashi Namisaki, Akira Mitoro, Hitoshi Yoshiji |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
congenital hereditary and neonatal diseases and abnormalities Heart disease medicine.medical_treatment liver cirrhosis transcatheter arterial embolization Case Report 030204 cardiovascular system & hematology Fontan procedure 03 medical and health sciences Liver disease 0302 clinical medicine Medicine 030212 general & internal medicine cardiovascular diseases lcsh:R5-920 business.industry spontaneous tumor rupture Fontan-associated liver disease General Medicine hepatocellular carcinoma medicine.disease Surgery Cardiac surgery Hepatocellular carcinoma cardiovascular system business lcsh:Medicine (General) |
| Zdroj: | SAGE Open Medical Case Reports, Vol 8 (2020) SAGE Open Medical Case Reports |
| Popis: | The prognosis of congenital heart disease is dramatically improved by cardiac surgery. The Fontan procedure is the definitive palliative operation for patients with single-ventricle physiology. In parallel with the longer survival time achieved with the Fontan procedure, the incidence of Fontan-associated liver disease is increasing. A 40-year-old man who underwent Fontan procedures at the ages of 9 was referred to our hospital for further evaluation of multiple hepatic tumors. Enhanced computed tomography showed large hepatocellular carcinomas with portal thrombi (Vp3). Spontaneous hepatocellular carcinoma rupture occurred 2 weeks after the first visit to our hospital, and emergent transcatheter arterial embolization of the hepatic artery was performed. Three months later, the patient died of liver failure. Autopsy findings showed moderately differentiated hepatocellular carcinoma with a cirrhotic liver characterized by centrilobular fibrosis and sinusoidal dilation similar to that in Fontan-associated liver disease. We reported the first case of spontaneously ruptured hepatocellular carcinoma treated by emergent transcatheter arterial embolization in Fontan-associated liver disease. As the early diagnosis of liver cirrhosis and hepatocellular carcinoma results in better patients’ outcome, cardiologists and hepatologists should be aware of Fontan-associated liver disease and advise patients to have regular follow-up of the liver. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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