Lost in the Clinics and Found in the Morgue: A Case of Peripheral T-cell Lymphoma Masquerading as Pneumonia
| Autor: | Vathany Sriganeshan, Jyotsna Kochiyil, Kritika Krishnamurthy, Claudio Tuda |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Modern medicine Systemic disease medicine.medical_specialty Fever Constitutional symptoms Autopsy Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine medicine Bronchopneumonia Humans 030216 legal & forensic medicine Diagnostic Errors Lung Aged business.industry Lymphoma T-Cell Peripheral Exanthema medicine.disease Dermatology Peripheral T-cell lymphoma Lymphoma Pneumonia business Tomography X-Ray Computed Generalized lymphadenopathy |
| Zdroj: | The American journal of forensic medicine and pathology. 41(4) |
| ISSN: | 1533-404X |
| Popis: | In modern medicine, there is an increasing dependence on noninvasive imaging modalities, for diagnosis and management of diseases. Though there are definite advantages to this, they are at times offset by diagnostic pitfalls especially in entities with elusive clinical presentation.Peripheral T-cell lymphoma-not otherwise specified (PTCL-NOS) is an aggressive subtype of T-cell lymphomas that does not meet criteria for a specific subtype. Peripheral T-cell lymphoma usually has varied clinical presentations depending on the site of involvement. Vast majority of PTCL patients present with systemic disease, generalized lymphadenopathy and constitutional symptoms. Pulmonary involvement is relatively rare and is seen in approximately 10% of patients.Here in we highlight a rare case of PTCL, masquerading as pneumonia due to extensive pulmonary involvement that went undiagnosed and was discovered at autopsy. This case of malignant lymphoma of T-cell origin involving the lung, which is very rare, highlights the continued importance of medical autopsies not only as a teaching tool but also as an important adjunct to investigative medicine in uncovering lapses that can subsequently be avoided to improve patient care and decrease mortality. |
| Databáze: | OpenAIRE |
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