Luteoma-induced fetal virilization
Autor: | Tadashi Kimura, Hiromi Ugaki, Takayuki Enomoto, Yoshihiro Tokugawa |
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Rok vydání: | 2009 |
Předmět: |
Adult
endocrine system medicine.medical_specialty Labial fusion Clitoromegaly Asymptomatic Lesion Pregnancy medicine Humans Testosterone Maternal-Fetal Exchange Ovarian Neoplasms Gynecology Tubal ligation Cesarean Section Luteoma business.industry Virilization Infant Newborn Obstetrics and Gynecology medicine.disease Virilism female genital diseases and pregnancy complications Female medicine.symptom business Pregnancy Complications Neoplastic |
Zdroj: | Journal of Obstetrics and Gynaecology Research. 35:991-993 |
ISSN: | 1447-0756 1341-8076 |
DOI: | 10.1111/j.1447-0756.2009.01046.x |
Popis: | A pregnancy luteoma represents an unusual response of ovarian stromal cells to the altered hormonal levels of pregnancy. It is a distinctive non-neoplastic lesion characterized by solid proliferations of luteinized cells resulting in a tumor-like ovarian enlargement. Most patients are asymptomatic; the ovarian enlargement is usually discovered incidentally at cesarean section or during postpartum tubal ligation. We report a typical case that we found at cesarean section to be associated with a virilized infant who manifested clitoromegaly and labial fusion. We detected an increased level of testosterone in the maternal patient. We concluded that the ovarian luteoma induced the fetal virilization. |
Databáze: | OpenAIRE |
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