Effect of the addition of epinephrine to a lidocaine solution on the efficacy and duration of palmar digital nerve blocks in horses with naturally occurring forefoot lameness
| Autor: | John Schumacher, Fred J. DeGraves, Ana Velloso Alvarez |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Heel Lidocaine Epinephrine 040301 veterinary sciences Lameness Animal Pain 0403 veterinary science Foot Diseases 03 medical and health sciences 0302 clinical medicine Heart rate Forelimb Medicine Animals Horses Anesthetics Local Gait Pain Measurement Cross-Over Studies General Veterinary business.industry Forefoot Horse Nerve Block 030206 dentistry 04 agricultural and veterinary sciences General Medicine Crossover study medicine.anatomical_structure Lameness Anesthesia Drug Therapy Combination Horse Diseases business medicine.drug |
| Zdroj: | American journal of veterinary research. 79(10) |
| ISSN: | 1943-5681 |
| Popis: | OBJECTIVE To determine whether addition of epinephrine to a lidocaine solution would prolong and potentiate the efficacy of a palmar digital nerve block (PDNB) in horses. ANIMALS 6 adult horses with naturally occurring forefoot lameness. PROCEDURES Initially, a PDNB with a 2% lidocaine solution was performed on the affected foot of each horse. Three days later, the PDNB was repeated with a 1% lidocaine solution or a 1% lidocaine solution containing epinephrine (dilution, 1:200,000). After another 3-day washout period, the PDNB was repeated with the treatment opposite that administered for the second PDNB. Gait was analyzed with a computerized lameness analysis system and heart rate and extent of skin sensation between the heel bulbs of the blocked foot were evaluated at predetermined times for 2 hours after each PDNB. RESULTS Efficacy and duration of the PDNB did not differ significantly between the 2% and 1% lidocaine treatments. The addition of epinephrine to the 1% lidocaine solution improved the efficacy and prolonged the duration of the PDNB. It also resulted in a positive correlation between skin desensitization and amelioration of lameness. Median heart rate remained unchanged throughout the observation period for all 3 treatments. No adverse effects associated with the PDNBs were observed. CONCLUSIONS AND CLINICAL RELEVANCE Addition of epinephrine (dilution, 1:200,000) to a 1% lidocaine solution improved the efficacy and prolonged the duration of a PDNB in horses with naturally occurring lameness and might be clinically useful for lameness evaluations and standing surgery of the forefoot of horses. |
| Databáze: | OpenAIRE |
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