Exploration of Potent Cytotoxic Molecules from Fungi in Recent Past to Discover Plausible Anticancer Scaffolds

Autor: Chaitrali Shevkar, Pranali Pradhan, Ashwini Armarkar, Komal Pandey, Kiran Kalia, Priyani Paranagama, Abhijeet S. Kate
Rok vydání: 2022
Předmět:
Zdroj: Chemistry & Biodiversity. 19
ISSN: 1612-1880
1612-1872
Popis: Fungi are known to produce diverse scaffolds possessing unique biological activities, however, to date, no molecule discovered from a fungal source has reached the market as an anti-cancer drug. Every year number of cytotoxic molecules of fungal origin are getting published and critical analysis of those compounds is necessary to identify the potent ones. A review mentioning the best cytotoxic fungal metabolites and their status in the drug development was published in 2014. In this report, we have included 176 cytotoxic molecules isolated from fungi after 2014 and categorized them according to their potencies such as IC
Databáze: OpenAIRE
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