Comparaciones indirectas en los informes de evaluación de medicamentos en la web del grupo GENESIS de la SEFH
| Autor: | A. Ortega Eslava, A. Clopés Estela, F. Puigventós Latorre, M.D. Fraga Fuentes, M. Vilanova Boltó, B. Santos-Ramos |
|---|---|
| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | Dadun. Depósito Académico Digital de la Universidad de Navarra instname |
| Popis: | Objective: Quantify use of indirect comparisons (IC) in drug evaluation reports published on the GENESIS Group web page for new drug assessment, standardisation, and drug selection research. Method: Retrospective study of drug reports written between 2008 and 2009. Data collected: presence of an active comparator and details from any direct and indirect comparative studies included. Results: An active comparator was present in 95% of the 337 analysed reports; 50% included a direct comparative study vs comparator. In 114 reports (34%), an IC was used; 69% of the ICs were made by the report author. Most ICs were narrative and none were adjusted. An IC could have been made in an additional 16% of the cases and possibly in 24% more. Conclusions: Most evaluated drugs have an active comparator but studies comparing them directly are not as common. ICs could be included in more reports along with quality control criteria. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|