| Autor: |
Alexandru Căciuleanu, Felix Vöhringer, Ivana Fleischer |
| Rok vydání: |
2023 |
| Předmět: |
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| DOI: |
10.26434/chemrxiv-2023-47qf9 |
| Popis: |
We report a catalytic system for direct deoxygenation of benzylic alcohols by using non-precious precatalyst Cp2TiCl2 and 2 MeTHF as solvent. Mechanistic studies showed that the used silane Me(EtO)2SiH acts both as H-donor and regenerating agent of the active catalytic species. This method tolerates a wide variety of functional and protecting groups and enables sequential deoxygenation-dehalogenation and deoxygenation-hydrogenation reactions. The procedure was successfully applied in the exhaustive reduction of lignin model substrates into value-added compounds. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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