Neutrophil‐lymphocyte and platelet‐lymphocyte ratios in otitis media with effusion in children: Diagnostic role and audiologic correlations
| Autor: | Ahmet Yukkaldiran, Mehmet Erkan Kaplama, Osman Erdoğan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Blood Platelets
medicine.medical_specialty Neutrophils Hearing loss 030204 cardiovascular system & hematology Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine otorhinolaryngologic diseases medicine Humans Lymphocytes 030212 general & internal medicine Mean platelet volume Child Retrospective Studies medicine.diagnostic_test Receiver operating characteristic Otitis Media with Effusion business.industry Complete blood count General Medicine Audiogram Serous fluid Otitis ROC Curve Pure tone audiometry medicine.symptom business Mean Platelet Volume |
| Zdroj: | International Journal of Clinical Practice. 75 |
| ISSN: | 1742-1241 1368-5031 |
| DOI: | 10.1111/ijcp.13805 |
| Popis: | Aim To investigate the relationship between hearing loss and complete blood count parameters including neutrophil, lymphocyte, platelet (PLT), mean platelet volume (MPV), neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in children with otitis media with effusion (OME). Materials-method The study group was formed by 244 paediatric patients who underwent ventilation tube placement because of OME, and was split into two groups as serous and mucoid. The control group included 112 individuals who have no hearing problems. Hearing levels were determined with pure tone audiometry in the study group, preoperatively, and control group. The blood parameters were compared between the serous, mucoid and control groups. The correlation analysis was performed between the blood parameters and hearing levels in the study group. The blood parameters were compared between the groups identified by hearing loss classification. Findings There were significant negative correlations between hearing levels and each of NLR, PLR and MPV. There were significant positive correlations between hearing levels and each of the lymphocyte and PLT. According to the receiver operating characteristic (ROC) curves, serous OME can be estimated with 68% sensitivity and 61% specificity by the NLR value more than 1.1, and 77% sensitivity and 77% specificity by the PLR value more than 102.4. The ROC curve revealed that slight hearing loss could be estimated with 70% sensitivity and 73% specificity by the NLR value more than 1.31, and 78% sensitivity and 77% specificity by the PLR value more than 102.4. Conclusion The present study revealed that NLR and PLR values were valuable parameters in the diagnosis of serous OME and predicting a hearing loss. These parameters may provide additional information to the audiogram that could influence the therapeutic decision. |
| Databáze: | OpenAIRE |
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