Clinical perspectives on the association between respiratory syncytial virus and reactive airway disease
| Autor: | Nele Sigurs |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Pulmonary and Respiratory Medicine
Allergy viruses respiratory syncytial virus Respiratory Tract Diseases Respiratory Syncytial Virus Infections Allergic sensitization Risk Factors medicine Genetic predisposition Respiratory Hypersensitivity Bronchiolitis Viral Humans Prospective cohort study Asthma lcsh:RC705-779 Reactive airway disease reactive airway disease business.industry Incidence (epidemiology) Infant lcsh:Diseases of the respiratory system respiratory system asthma medicine.disease allergy Hospitalization Bronchiolitis Immunology bronchiolitis business Supplement |
| Zdroj: | Respiratory Research Respiratory Research, Vol 3, Iss Suppl 1, Pp S8-S14 (2002) |
| ISSN: | 1465-993X 1465-9921 |
| Popis: | Asthma is a leading cause of morbidity and mortality among children worldwide, as is respiratory syncytial virus (RSV). This report reviews controlled retrospective and prospective studies conducted to investigate whether there is an association between RSV bronchiolitis in infancy and subsequent development of reactive airway disease or allergic sensitization. Findings indicate that such a link to bronchial obstructive symptoms does exist and is strongest for children who experienced severe RSV illness that requires hospitalization. However, it is not yet clear what roles genetic predisposition and environmental or other risk factors may play in the interaction between RSV bronchiolitis and reactive airway disease or allergic sensitization. Randomized, prospective studies utilizing an intervention against RSV, such as a passive immunoprophylactic agent, may determine whether preventing RSV bronchiolitis reduces the incidence of asthma. |
| Databáze: | OpenAIRE |
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