Application of Pet-CT Fusion Deep Learning Imaging in Precise Radiotherapy of Thyroid Cancer
| Autor: | Sen Hou, Zhen Chen, Qian-Le Qi, Qiuyu Lin, Lan Zhang, Chenghe Lin, Nan Jiang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Medicine (General)
Article Subject medicine.medical_treatment Biomedical Engineering Health Informatics Standardized uptake value Physical examination Metastasis Iodine Radioisotopes Deep Learning R5-920 Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography medicine Medical technology Humans Thyroid Neoplasms R855-855.5 Thyroid cancer PET-CT medicine.diagnostic_test business.industry Thyroid medicine.disease Imaging agent Radiation therapy medicine.anatomical_structure Surgery Tomography X-Ray Computed Nuclear medicine business Research Article Biotechnology |
| Zdroj: | Journal of Healthcare Engineering, Vol 2021 (2021) Journal of Healthcare Engineering |
| ISSN: | 2040-2295 |
| DOI: | 10.1155/2021/2456429 |
| Popis: | This article explores the value of wall F-FDG PET/Cr imaging in the diagnosis of thyroid cancer, studies its ability to distinguish benign and malignant thyroid lesions, and seeks ways to improve the accuracy of diagnosis. The normal control group selected 40 patients who came to our center for physical examination. In the normal control group, the average value of the standard uptake value of both sides of the thyroid was used as the SUV of the thyroid gland and the highest SUV value of the patient's lesion (SUV max) represented the SUV of the lesion. After injection of imaging agent 18F-FD1G, routine imaging was performed at 1h, time-lapse imaging was performed at 2.5 h, and the changes with conventional imaging were compared to infer the benign and malignant lesions. We used SPSS software to carry out statistical analysis, respectively, carrying out analysis of variance, paired t-test, independent sample t-test, and linear correlation analysis. In the thyroid cancer group, 87.5% of the delayed imaging SUV was higher than the conventional imaging SUV, while 83.33% of the benign disease group had a lower SUV than the conventional imaging SUV. 18F-FDG PET/CT imaging has higher sensitivity and specificity for the diagnosis of recurrence or metastasis in patients with Tg positive. However, it has lower sensitivity and specificity for the diagnosis of 131I-Dx-WBS negative DTC and 18F-FDG PET/CT. The specificity increases with the increase of serum Tg level. The above results confirm that 18F-FDG PET/CT imaging is of great significance for the diagnosis of recurrence or metastasis in patients; with PET/CT imaging, the results changed 16.13% of the Tg-positive and 131I-Dx-WBS negative DTC patients' later treatment decision. The decision-making and curative effect evaluation have certain value. |
| Databáze: | OpenAIRE |
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