Plasma extracellular vesicle protein content for diagnosis and prognosis of global cardiovascular disease
| Autor: | Dominique P.V. de Kleijn, Jiong-Wei Wang, A. Mosterd, Crystel M. Gijsberts, Arthur Mark Richards, Leo Timmers, Mark Y. Chan, Chuen Neng Lee, V. C. de Hoog, Aruni Seneviratna, Siu Kwan Sze, Gerard Pasterkamp, Sai Kiang Lim, A.H. Schoneveld, Carolyn S.P. Lam, Joyce E. P. Vrijenhoek |
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| Přispěvatelé: | School of Biological Sciences |
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
business.industry Public health Ethnic group Disease Extracellular vesicle Bioinformatics medicine.disease Biobank Obesity Protein content Science::Biological sciences::Human anatomy and physiology [DRNTU] Diabetes mellitus Medicine Icin Cardiology and Cardiovascular Medicine business |
| Zdroj: | Netherlands Heart Journal |
| ISSN: | 1876-6250 1568-5888 |
| DOI: | 10.1007/s12471-013-0462-3 |
| Popis: | Cardiovascular disease is a major public health problem worldwide. Its growing burden is particularly ominous in Asia, due to increasing rates of major risk factors such as diabetes, obesity and smoking. There is an urgent need for early identification and treatment of individuals at risk of adverse cardiovascular events. Plasma extracellular vesicle proteins are novel biomarkers that have been shown to be useful in the diagnosis, risk stratification and prognostication of patients with cardiovascular disease. Ongoing parallel biobank initiatives in European (the Netherlands) and Asian (Singapore) populations offer a unique opportunity to validate these biomarkers in diverse ethnic groups. Published version |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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