Evaluation of SARS-CoV-2 viral RNA in fecal samples
| Autor: | Antonella Cima, Davide Sparacino, Katia Margiotti, Antonella Viola, Alvaro Mesoraca, Claudio Giorlandino |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Time Factors Genes Viral Pneumonia Viral Respiratory System Short Report 010501 environmental sciences Biology medicine.disease_cause 01 natural sciences Virus lcsh:Infectious and parasitic diseases Betacoronavirus Feces 03 medical and health sciences Virology medicine Humans lcsh:RC109-216 Viral shedding Respiratory system Pandemics Respiratory specimens 0105 earth and related environmental sciences Coronavirus SARS-CoV-2 Fecal specimens SARS-CoV-2 viral RNA COVID-19 RNA biology.organism_classification Virus Shedding 030104 developmental biology Infectious Diseases medicine.anatomical_structure Molecular Diagnostic Techniques Acute respiratory syndrome coronavirus 2 Novel coronavirus disease 19 Acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA Viral Female Coronavirus Infections Novel coronavirus disease 19 (COVID-19) Respiratory tract |
| Zdroj: | Virology journal, 17(1):86 Virology Journal, Vol 17, Iss 1, Pp 1-3 (2020) Virology Journal |
| Popis: | The need for timely establishment of a complete diagnostic protocol of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is demanded worldwide. We selected 15 positive novel coronavirus disease 19 (COVID-19) patients with mild or no symptom. Initially, fecal samples were negative in the 67% (10/15) of the cases, while 33% (5/10) of the cases were positive. After serial virus RNA testing, 73% (11/15) of the cases resulted positive to fecal specimens. In particular, 15 days after the first positive respiratory specimens test, 6 fecal specimens became positive for SARS-CoV-2 RNA, while 13 respiratory test returned negative result. In conclusion, qRT-PCR assays of fecal specimens, is an important step to control infection, suggesting that samples remained positive for SARS-CoV-2 RNA longer time then respiratory tract samples. Our results enhance the recent knowledge on this emerging infectious disease and offer suggestions for a more complete diagnostic strategy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|