Analysis of the temporal change in biophysical parameters after fractional laser treatments using reflectance confocal microscopy
| Autor: | Sang Jun Lee, Mu-Hyoung Lee, Min-Joong Kim, Mi-Ae Yoo, Jae-Sook Koh, Min Kyung Shin, Ji-Hwoon Baek |
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| Rok vydání: | 2012 |
| Předmět: |
Reflectance confocal microscopy
Adult medicine.medical_specialty Photoaging Fractional laser Dermoscopy Dermatology Lasers Solid-State Biophysical Phenomena Young Adult Asian People medicine Humans Rejuvenation Temporal change Low-Level Light Therapy Transepidermal water loss Microscopy Confocal integumentary system Photorejuvenation Chemistry Dermis medicine.disease Water Loss Insensible Elasticity Skin Aging Dermal papillae medicine.anatomical_structure Treatment Outcome Female Skin roughness Biomedical engineering |
| Zdroj: | Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). 19(1) |
| ISSN: | 1600-0846 |
| Popis: | Background Fractional photothermolysis is a popular treatment option for photorejuvenation. Previous literature studies have demonstrated the clinical effectiveness of fractional photothermolysis on cutaneous photoaging; however, the associated changes in biophysical properties of the skin following fractional photothermolysis have not been fully elucidated. This study was conducted to investigate the temporal changes in biophysical parameters after fractional laser treatment on Asian skin. Materials and Methods Eleven female subjects underwent a single treatment with an erbium glass fractional laser. Skin roughness, elasticity, transepidermal water loss (TEWL), dermal thickness were evaluated before and immediately after treatment and 3 days, 1 week, 2 weeks, and 4 weeks after treatment. The changes in the dermal papilla were analyzed using a reflectance confocal microscopy (RCM). Results Skin roughness showed the greatest improvement at the first week and net elasticity was most improved at the second week. TEWL and the percentage of melanized and active dermal papillae (DP) were mostly increased for 3 days. At 4 weeks after treatment, the number of total dermal papillae showed a significant increase compared with pretreatment. Conclusion This is the first study of the characterization and quantification of dermal papilla reflecting the dermal repair process after fractional photothermolysis through an RCM. |
| Databáze: | OpenAIRE |
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