Incidence and Risk Factors of Ocular Hypertension and Glaucoma in Patients With Acanthamoeba Keratitis
| Autor: | Shaimaa Alrefaie, Adi Mohammed Al Owaifeer, Sarah Al-Omair, Saad H Alenezi, Sami Al-Shahwan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Intraocular pressure
medicine.medical_specialty Visual acuity genetic structures Glaucoma Ocular hypertension Risk Factors Ophthalmology Medicine Humans Intraocular Pressure Retrospective Studies business.industry Incidence (epidemiology) Incidence Retrospective cohort study Odds ratio medicine.disease eye diseases Regimen Acanthamoeba Keratitis Ocular Hypertension sense organs medicine.symptom business |
| Zdroj: | Eyecontact lens. 47(11) |
| ISSN: | 1542-233X |
| Popis: | Objectives To determine the incidence of ocular hypertension (OHT) and glaucoma in patients with acanthamoeba keratitis (AK) and to outline the risk factors for the development of glaucoma. Methods A retrospective review of patients diagnosed with AK at our institute during the period from 2000 to 2018. The main outcome measures were the incidence of OHT and glaucoma, and risk factors for the development of glaucoma. Results Fifty-two eyes diagnosed with AK were included. The incidence of OHT and glaucoma was 51.9% and 32.7%, respectively. The mean duration from disease onset to the first attack of elevated intraocular pressure was 8.4±16.6 months. The use of corticosteroids in the treatment regimen was significantly associated with the development of glaucoma (odds ratio, 3.93; 95% confidence interval, 0.96-16.15; P=0.049). At the last follow-up visit, both patients with glaucoma and nonglaucoma patients had improved visual acuity without a difference in the mean amount of logarithm of the minimum angle of resolution acuity improvement among them (0.56±0.91 vs. 0.67±0.87, P=0.686). Conclusion Our findings confirm that OHT and glaucoma are frequent complications in AK. Patients treated with a regimen containing corticosteroids are at a higher risk; thus, they should receive close intraocular pressure monitoring. |
| Databáze: | OpenAIRE |
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