Pre-operative assessment of basal cell carcinoma dimensions using high frequency ultrasonography and its correlation with histopathology
| Autor: | Maryam Sarraf-Yazdy, Ferial Fanian, Mohammad-Mehdi Naghizadeh, Pedram Noormohammadpour, Mostafa Mirshams Shahshahani, Alireza Firooz, Mansour Nassiri-Kashani, Hamed Zartab, Kambiz Kamyab, Bardia Sadr |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Skin Neoplasms Biopsy Dermatology Correlation Preoperative Care medicine Carcinoma Humans High frequency ultrasonography Basal cell carcinoma Postoperative Period Aged Ultrasonography medicine.diagnostic_test business.industry Ultrasound Reproducibility of Results Middle Aged Reference Standards medicine.disease Carcinoma Basal Cell Female Histopathology business Nuclear medicine |
| Zdroj: | Skin Research and Technology. 19:e132-e138 |
| ISSN: | 0909-752X |
| DOI: | 10.1111/j.1600-0846.2012.00619.x |
| Popis: | Fasa University of Medical Sciences, Fasa, IranIntroduction: High frequency ultrasonography (HFUS) is anon-invasive, low risk method which can provide real-timevisual information regarding different processes in cutaneoustissue. The goal of this study is to compare the accuracy ofHFUS in determining depth and width of basal cell carcinoma(BCC) lesions compared with histopathology as a referencestandard.Methods: The depth and width of 56 primary BCCs in variouslocations were measured in vivo using the ultrasound systemdevice Digital Taberna Promedica (Luneburg, FRG DUB 20Ultrasound Scanner), with a 50-MHz hand-held transducer andcompared with the depth and width reported in histopathologicexamination of these lesions after complete excision. The intra-class correlation coefficient (ICC) was calculated using a one-way ANOVA table to compare measured dimensions for thesame tumors with the two diagnostic methods.Results: The mean depth of tumor in HFUS(1353.68 ± 656.456 microns) was lower than the amount mea-sured by the dermatopathologist (1560.71 ± 1044.323microns). However, the difference was not statistically signifi-cant (P > 0.05). The means of largest diameter of tumors inHFUS and pathology were 5996.77 ± 2271.783 and3891.07 ± 1995.452 microns, respectively (P < 0.001). Therewas a low correlation in diameter (r = 0.27, P < 0.05) and amoderate correlation in depth (r = 0.45, P < 0.001) of BCCsbetween these two methods.Conclusion: HFUS may be a useful method to assess thedimensions of BCC prior to surgery.Key words: skin cancer – diagnosis – imaging – high fre-quency ultrasonography – dimension – basal cell carcinoma |
| Databáze: | OpenAIRE |
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