Dietary Isoflavone-Dependent and Estradiol Replacement Effects on Body Weight in the Ovariectomized (OVX) Rat
| Autor: | Margaret F. Keil, Joanna Westerfield, Michael R. Landauer, Ashley L. Russell, Lawren Wooten, T. John Wu, Robert J. Handa, Darwin O. Larco, Danette F. Cruthirds, Jamie Grimes, Michael J. Weiser |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Hormone Replacement Therapy Ovariectomy Endocrinology Diabetes and Metabolism Clinical Biochemistry Abdominal Fat Drinking Energy metabolism Biology Body weight Biochemistry Article Rats Sprague-Dawley 03 medical and health sciences chemistry.chemical_compound Endocrinology Adipokines Internal medicine medicine Hormone replacement therapy (male-to-female) Animals Estradiol Leptin Body Weight Uterus Biochemistry (medical) Feeding Behavior Organ Size General Medicine Isoflavones Diet 030104 developmental biology chemistry Estrogenic Effects Ovariectomized rat Cytokines Female medicine.symptom Weight gain |
| Zdroj: | Hormone and Metabolic Research. 49:457-465 |
| ISSN: | 1439-4286 0018-5043 |
| Popis: | 17β-Estradiol is known to regulate energy metabolism and body weight. Ovariectomy results in body weight gain while estradiol administration results in a reversal of weight gain. Isoflavones, found in rodent chow, can mimic estrogenic effects making it crucial to understand the role of these compounds on metabolic regulation. The goal of this study is to examine the effect of dietary isoflavones on body weight regulation in the ovariectomized rat. This study will examine how dietary isoflavones can interact with estradiol treatment to affect body weight. Consistent with previous findings, animals fed an isoflavone-rich diet had decreased body weight (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|