Accuracy of risk prediction scores in pregnant women with congenital heart disease

Autor: Morgan Venuti, Sara L. Partington, Adi Hirshberg, Katherine Awh, Yuli Y. Kim, Lisa D. Levine, Tanmay Bhamare, David Drajpuch, Rachel Rogers, Lynda Tobin, Leah A. Goldberg, Emily Ruckdeschel
Rok vydání: 2018
Předmět:
Adult
Heart Defects
Congenital

medicine.medical_specialty
Time Factors
Heart disease
Adolescent
Population
Pregnancy Complications
Cardiovascular

030204 cardiovascular system & hematology
Lower risk
Risk Assessment
Article
Decision Support Techniques
03 medical and health sciences
Young Adult
0302 clinical medicine
Predictive Value of Tests
Pregnancy
Risk Factors
030225 pediatrics
Internal medicine
medicine
Humans
Radiology
Nuclear Medicine and imaging

Myocardial infarction
education
Stroke
Tetralogy of Fallot
Retrospective Studies
education.field_of_study
business.industry
Pregnancy Outcome
Retrospective cohort study
General Medicine
medicine.disease
Maternal Mortality
Heart failure
Pediatrics
Perinatology and Child Health

Cardiology
Surgery
Female
Cardiology and Cardiovascular Medicine
business
Zdroj: Congenit Heart Dis
ISSN: 1747-0803
Popis: OBJECTIVE: To assess performance of risk stratification schemes in predicting adverse cardiac outcomes in pregnant women with congenital heart disease and to compare these schemes to clinical factors alone. DESIGN: Single-center retrospective study SETTING: Tertiary care academic hospital PATIENTS: Women ≥ 18 years with International Classification of Diseases, Ninth Revision, Clinical Modification codes indicating congenital heart disease who delivered between 1998 and 2014. CARPREG I and ZAHARA risk scores and modified World Health Organization (WHO) criteria were applied to each woman. OUTCOME MEASURES: The primary outcome was defined by ≥1 of the following: arrhythmia, heart failure/pulmonary edema, transient ischemic attack, stroke, dissection, myocardial infarction, cardiac arrest, death during gestation and up to 6 months post-partum. RESULTS: Of 178 women, the most common congenital heart disease lesions were congenital aortic stenosis (15.2%), ventricular septal defect (13.5%), atrial septal defect (12.9%), and tetralogy of Fallot (12.9%). Thirty-five women (19.7%) sustained 39 cardiac events. Observed vs. expected event rates were 9.9% vs 5% (p=0.02) for CARPREG I score 0 and 26.1% vs. 7.5% (p
Databáze: OpenAIRE