Prospective study of the association of serum triglyceride and glucose with colorectal cancer
| Autor: | James Lee, Abraham M. Y. Nomura, Grant N. Stemmermann, Matthew Tsushima |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Alcohol Drinking Physiology Colorectal cancer Gastroenterology Risk Assessment Body Mass Index Cohort Studies chemistry.chemical_compound Age Distribution Internal medicine medicine Biomarkers Tumor Confidence Intervals Humans Prospective Studies Sex Distribution Prospective cohort study Triglycerides Aged Neoplasm Staging Probability Proportional Hazards Models Triglyceride Asian business.industry Proportional hazards model Incidence Smoking Hepatology Middle Aged medicine.disease Survival Analysis United States Endocrinology chemistry Relative risk Female business Colorectal Neoplasms Body mass index Cohort study |
| Zdroj: | Digestive diseases and sciences. 50(3) |
| ISSN: | 0163-2116 |
| Popis: | To determine if serum triglyceride and glucose levels are associated with colorectal cancer, a prospective study among 7619 Japanese-American men was conducted. From 1968 to 1998, 376 colon and 124 rectal cancer incident cases were diagnosed. A strong positive association of alcohol intake and pack-years of cigarette smoking with colorectal cancer was observed. Body mass index and heart rate were also positively related to colon, but not to rectal cancer. In contrast, serum triglyceride did not predict the development of either colon or rectal cancer. There was a modest association of serum glucose in the highest quartile group with rectal cancer (relative risk = 1.33; 95% confidence interval, 0.79-2.26), but it was not statistically significant. This study did not find a strong positive association of serum triglyceride or glucose with colorectal cancer, but additional studies including other metabolic consequences associated with increased serum triglyceride and glucose may clarify the relationship. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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