Physiological Closed-Loop Control (PCLC) Systems: Review of a Modern Frontier in Automation

Autor: Nader Jalili, Mohammad Javad Khodaei, Amin Mehrvarz, Nicholas Candelino
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Control theory (sociology)
0209 industrial biotechnology
Engineering
General Computer Science
media_common.quotation_subject
Medical equipment
030209 endocrinology & metabolism
02 engineering and technology
Systems and Control (eess.SY)
anesthesia
Electrical Engineering and Systems Science - Systems and Control
Quantitative Biology - Quantitative Methods
Field (computer science)
03 medical and health sciences
020901 industrial engineering & automation
0302 clinical medicine
Control theory
Multidisciplinary approach
FOS: Electrical engineering
electronic engineering
information engineering

General Materials Science
Quality (business)
automated anesthesia
Quantitative Methods (q-bio.QM)
media_common
automation
business.industry
artificial pancreas
General Engineering
Adaptive control
artificial intelligence
Automation
Work (electrical)
FOS: Biological sciences
lcsh:Electrical engineering. Electronics. Nuclear engineering
business
lcsh:TK1-9971
Systems pharmacology
Zdroj: IEEE Access, Vol 8, Pp 23965-24005 (2020)
ISSN: 2169-3536
Popis: Over the past decade, there has been an unprecedented international focus on improved quality and availability of medical care, which has reignited interest in clinical automation and drawn researchers toward novel solutions in the field of physiological closed-loop control systems (PCLCs). Today, multidisciplinary groups of expert scientists, engineers, clinicians, mathematicians, and policy-makers are combining their knowledge and experience to develop both the next generation of PCLC-based medical equipment and a collaborative commercial/academic infrastructure to support this rapidly expanding frontier. In the following article, we provide a robust introduction to the various aspects of this growing field motivated by the recent and ongoing work supporting two leading technologies: the artificial pancreas (AP) and automated anesthesia. Following a brief high-level overview of the main concepts in automated therapy and some relevant tools from systems and control theory, we explore -- separately -- the developments, challenges, state-of-the-art, and probable directions for AP and automated anesthesia systems. We then close the review with a consideration of the common lessons gleaned from these ventures and the implications they present for future investigations and adjacent research.
39 pages, 13 figures
Databáze: OpenAIRE