Diagnostic open brain biopsy following initial negative results of cerebrospinal fluid assessment for Toxoplasma

Autor: Takeshi Kobayashi, Noriko Doki, Yasushi Senoo, Kazuteru Ohashi, Kazuhiko Kakihana, Noritaka Sekiya, Hisashi Sakamaki, Aiko Igarashi, Kosuke Yoshioka, Takeshi Hagino, Shugo Sasaki, Hideharu Muto, Yuho Najima, Kyoko Watakabe-Inamoto
Rok vydání: 2016
Předmět:
0301 basic medicine
Adult
Male
Pathology
medicine.medical_specialty
Transplantation Conditioning
Fever
Vomiting
medicine.medical_treatment
Biopsy
030106 microbiology
Hematopoietic stem cell transplantation
Polymerase Chain Reaction
03 medical and health sciences
Cerebrospinal fluid
Leukemia
Myelogenous
Chronic
BCR-ABL Positive
Trimethoprim
Sulfamethoxazole Drug Combination
medicine
Humans
Transplantation
Homologous
Pathological
Cyclophosphamide
Transplantation
medicine.diagnostic_test
business.industry
Antemortem Diagnosis
Headache
Hematopoietic Stem Cell Transplantation
Brain
Antibiotic Prophylaxis
Myeloablative Agonists
medicine.disease
Magnetic Resonance Imaging
Anti-Bacterial Agents
surgical procedures
operative
Infectious Diseases
Toxoplasmosis
Cerebral
Complication
business
Toxoplasma
Encephalitis
Zdroj: Transplant infectious disease : an official journal of the Transplantation Society. 19(2)
ISSN: 1399-3062
Popis: Cerebral toxoplasmosis is a rare but fatal complication after allogeneic hematopoietic stem cell transplantation (HSCT), and reaching an accurate antemortem diagnosis with pathological proof is difficult.1,2 We describe herein the clinical course of a patient with cerebral toxoplasmosis following allogeneic HSCT. The diagnosis was successfully made by aggressive open brain biopsy following initial negative results from cerebrospinal fluid (CSF) assessment for Toxoplasma. This article is protected by copyright. All rights reserved.
Databáze: OpenAIRE
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