Oral manifestations of a sinus melanoma: case report and literature review
| Autor: | Bertrand Fleury, Anne-Gaëlle Bodard, Candice Lesage, Mélanie Le Donne |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.medical_treatment lcsh:Surgery Malignancy 03 medical and health sciences 0302 clinical medicine pigmentation of the oral mucosa Medicine Dentistry (miscellaneous) mucosal melanoma Oral mucosa Sinus (anatomy) Chemotherapy business.industry Melanoma Mucosal melanoma lcsh:RD1-811 medicine.disease Dermatology Radiation therapy lcsh:RK1-715 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis lcsh:Dentistry sinus melanoma Etiology Periodontics Oral Surgery business |
| Zdroj: | Journal of Oral Medicine and Oral Surgery, Vol 25, Iss 4, p 35 (2019) |
| ISSN: | 2608-1326 |
| Popis: | Introduction: Mucosal melanoma (MM) is a rare malignancy of the head and neck. Sinonasal melanomas are the most frequent, followed by oral melanomas. Observation: A 67-year-old patient with a known left sinus melanoma initially treated with immunotherapy was referred for consultation concerning mobile teeth. A pigmented lesion infiltrating the left maxillary arch in the molar area was detected. The malignancy had invaded the oral mucosa. Despite many proposed treatments (immunotherapy, chemotherapy, and radiotherapy), the patient showed metastatic progression, which resulted in death. Discussion: Sinus MMs are malignancies with poor prognosis because these are often diagnosed in the late stages of disease progression. As these tumors are rare, there is no treatment consensus and surgery remains the best option. Diagnosis of pigmented lesions of the oral mucosa is sometimes complicated because of various implied etiologies. Conclusion: This case report shows that sinus MMs can induce pigmentation in the oral mucosa. These are rare malignancies with poor prognosis, for which no treatment consensus exists to date. |
| Databáze: | OpenAIRE |
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