Intraoperative ultrasound in conservative surgery for non-palpable breast cancer after neoadjuvant chemotherapy
| Autor: | Teresa L. Ramos, M. Sancho, J.C. Díez, R. Ruano, J.M. González-Orús, M. Ramos |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Reoperation medicine.medical_specialty Breast surgery medicine.medical_treatment Breast Neoplasms Mastectomy Segmental Neoadjuvant chemotherapy Lesion Breast cancer medicine Humans Mammography Ultrasonography Interventional Neoadjuvant therapy Aged Chemotherapy Intraoperative Care medicine.diagnostic_test business.industry Ultrasound General Medicine Middle Aged medicine.disease Non-palpable Complete clinical response Neoadjuvant Therapy Surgery Intraoperative ultrasound localization Carcinoma Lobular Chemotherapy Adjuvant Feasibility Studies Female Ultrasonography Mammary medicine.symptom business Mastectomy Re-excision rate |
| Zdroj: | International Journal of Surgery. 12(6):572-577 |
| ISSN: | 1743-9191 |
| DOI: | 10.1016/j.ijsu.2014.04.003 |
| Popis: | AimsA complete clinical response after neoadjuvant chemotherapy (NACT) in breast cancer patients hinders the localization of the residual lesion and the removal of a minimum amount of breast tissue. The aim of the present work is to report our single-centre experience with intraoperative ultrasound-guided (IOUS) excision performed by surgeons in these patients.Patients and methodsFrom January 2008 to December 2012, IOUS excisions were performed on 58 patients with a previous intralesional ultrasound-detectable metallic marker and non-palpable breast cancer after NACT. The specimen margins were estimated by ultrasonography and macroscopic pathologic examination. Successful lesion removal, specimen weight, and analysis of the results as regards margins were evaluated, and the need for breast-conserving re-excision and mastectomy was considered.ResultsAfter NACT the average ultrasound/mammography and MRI diameters were 11.7 mm (0–30) and 9.1 mm (0–40) respectively. In all cases, the residual lesion or tissue around the marker was removed. The average weight of the specimens was 26.4 g (6–84), being lower in cases of complete response according to ultrasound (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect