Normal perfusion pressure hyperperfusion in cerebral arteriovenous malformation surgery: model study on the hemodynamics and mechanisms

Autor: Yuichi Tada, Shiro Nagasawa, Sachiko Kajimoto, Tomio Ohta, Susumu Kondoh, Kazunobu Yamaguchi, Masahiro Kawanishi
Rok vydání: 1998
Předmět:
Zdroj: Journal of Clinical Neuroscience. 5:30-32
ISSN: 0967-5868
DOI: 10.1016/s0967-5868(98)90007-8
Popis: A simulation study was undertaken using a compartmental flow model of a large high-flow cerebral arteriovenous malformation to investigate the hemodynamic changes during obliteration procedures. Under certain autoregulatory conditions, marked hyperperfusion (92 ml/100 g/min) could be induced in association with increased wall stress of the arterioles. Narrowing of the autoregulatory pressure range and its shift to a low pressure level are suspected to be among the possible causes of normal perfusion pressure breakthrough phenomenon.
Databáze: OpenAIRE