Glomerulonephritis in NZW Kidneys Grafted into NZB/W Mice
| Autor: | K. Inoue, B. Albini, N. Niesen, F. Milgrom |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Graft Rejection
medicine.medical_specialty Pathology Ratón medicine.medical_treatment Immunology Autopsy Antigen-Antibody Complex Kidney Mice Glomerulonephritis Animal model immune system diseases Internal medicine medicine Animals Transplantation Homologous Immunology and Allergy Mice Inbred NZB urogenital system business.industry Histology General Medicine medicine.disease Kidney Transplantation Nephrectomy Transplantation Endocrinology medicine.anatomical_structure Hybridization Genetic business |
| Zdroj: | International Archives of Allergy and Immunology. 96:355-357 |
| ISSN: | 1423-0097 1018-2438 |
| DOI: | 10.1159/000235521 |
| Popis: | After left nephrectomy, 3 10-week old NZB/W mice received orthotopic grafts of kidneys from parental NZW mice of the same age. At autopsy conducted at the age of 33–38 weeks, glomerulonephritis of similar extent was noted in the recipients’ own and in the grafted kidneys. Also, very similar granular deposits of immunoglobulins and complement were demonstrated in these kidneys. It was concluded that the absence of glomerulonephritis in NZW mice cannot be attributed to the refractoriness of their kidney to this disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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