Language impairment and rate of cognitive decline in Alzheimer's disease
| Autor: | Catherine Tzortzis, Michel Panisset, François Boller, Marie-Claire Goldblum, Jean-Luc Michot |
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| Rok vydání: | 1994 |
| Předmět: |
Male
Longitudinal study medicine.medical_specialty Cognitive Neuroscience Disease Audiology Neuropsychological Tests Developmental psychology Primary progressive aphasia Degenerative disease Alzheimer Disease medicine Humans Language disorder Cognitive decline Aged Aged 80 and over Language Disorders Cognitive disorder medicine.disease Psychiatry and Mental health Female Geriatrics and Gerontology Alzheimer's disease Psychology Cognition Disorders |
| Zdroj: | Dementia (Basel, Switzerland). 5(6) |
| ISSN: | 1013-7424 |
| Popis: | There is growing evidence that AD consists of different subtypes, and that language is a pertinent factor to identify a subgroup with a fast rate of cognitive decline. We report the first results of a longitudinal study in which we compared two groups of patients with probable AD. The main result showed that a subgroup with stable MMSE scores during a 1-year follow-up period had an impairment in language domains which are usually preserved until an advanced stage of the disease. It is proposed that this group may correspond to a variety of AD who, in addition to symptoms of AD, present characteristics of primary progressive aphasia. In other respects, we underscore that the high loading in language-mediated tasks of the MMSE makes it a poor index to accurately measure the rate of cognitive decline. |
| Databáze: | OpenAIRE |
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