Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton

Autor: Phoebe Sussana Primus, Carol Hsin-Yi Wu, Chai-Lin Kao, Yeun-Mun Choo
Rok vydání: 2022
Předmět:
Zdroj: Natural Product Research. :1-8
ISSN: 1478-6427
1478-6419
Popis: Two new bisanthraquinones, glabraquinone A and B (1–2) were isolated from the root of Prismatomeris glabra (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (3), 1,2-dimethoxy-7-methylanthraquinone (4), lucidin (5), nordamnacanthal (6), damnacanthal (7) and 2-carboxaldehyde-3-hydroxyanthraquinone (8)) and an aromatic compound, that is, catechol diethyl ether (9) were isolated and characterized in this study. Compounds 1, 4 and 9 showed mild activity, reducing N2A cell viability to 77%, 82% and 77%, respectively, in anti-neuroblastoma assay.
Databáze: OpenAIRE