Veralipride for Hot Flushes during Gonadotropin-Releasing Hormone Agonist Treatment
| Autor: | Pier Giorgio Crosignani, Cristina Passadore, Paolo Vercellini, Alberto Colombo, Laura Trespidi, Nicoletta Vendola |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Agonist medicine.medical_specialty medicine.drug_class medicine.medical_treatment Endometriosis Gonadotropin-releasing hormone agonist Internal medicine Flushing medicine Humans Menorrhagia Chemotherapy Estradiol business.industry Goserelin Obstetrics and Gynecology Luteinizing Hormone Middle Aged medicine.disease Prolactin Clinical trial Endocrinology Reproductive Medicine Anesthesia Drug Therapy Combination Female Follicle Stimulating Hormone Sulpiride business Hormone medicine.drug Veralipride |
| Zdroj: | Gynecologic and Obstetric Investigation. 34:102-104 |
| ISSN: | 1423-002X 0378-7346 |
| DOI: | 10.1159/000292736 |
| Popis: | Hot flushes are the commonest symptom induced by gonadotropin-releasing hormone agonists (GnRHa). We performed an open observational trial to evaluate the efficacy of veralipride, an antidopaminergic drug, in reducing hot flushes in 25 premenopausal women treated with a GnRHa for endometriosis (8 subjects) or menorrhagia (17 subjects). The patients received goserelin depot for 6 months and veralipride was added for the third month. Hot flushes, severe in all women at 2 months, improved in both frequency and intensity in 92% of the subjects during veralipride administration. The benefit obtained persisted until the end of the GnRHa treatment. |
| Databáze: | OpenAIRE |
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