An Expedited Palliative Radiation Protocol for Lytic or Proliferative Lesions of Appendicular Bone in Dogs
| Autor: | Rance K. Sellon, Patrick R. Gavin, Heather M Knapp-Hoch, Janean Fidel |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Osteosarcoma medicine.medical_specialty business.industry Treatment outcome Pain relief Pain Bone Neoplasms Retrospective cohort study Kaplan-Meier Estimate Surgery Dogs Treatment Outcome Lytic cycle Median time Bone lesion Palliative radiation Animals Medicine Female Dog Diseases Small Animals business Median survival Retrospective Studies |
| Zdroj: | Journal of the American Animal Hospital Association. 45:24-32 |
| ISSN: | 1547-3317 0587-2871 |
| DOI: | 10.5326/0450024 |
| Popis: | Fifty-eight dogs with lytic or proliferative bone lesions were treated with a radiation protocol of two 8-Gy fractions over 2 consecutive days. The protocol was well tolerated, with no increase in early or late effects over previously published protocols. Forty-three (91%) of 47 dogs responded positively to radiation, with a median time of 2 days to onset of pain relief. Median duration of pain relief was 67 days (range 12 to 503 days; mean 99±16 days). Median survival time for all dogs was 136 days (mean 179±18 days). Distal radial location was a positive prognostic indicator for survival (P=0.005). |
| Databáze: | OpenAIRE |
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