e-Monitoring of Asthma Therapy to Improve Compliance in children (e-MATIC): a randomised controlled trial
| Autor: | Bart Wolf, Ellen I.M. Blankman, Monique Theodora Maria Veenstra-van Schie, Arnold G. Vulto, Liset van Dijk, Lucas M A Goossens, Erwin C. Vasbinder, Patricia M. L. A. van den Bemt, Nordin Dahhan, Hettie M. Janssens, Brenda C. M. de Winter, Maureen P.M.H. Rutten-van Mölken, Florens G. A. Versteegh |
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| Přispěvatelé: | AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, APH - Amsterdam Public Health, General Paediatrics |
| Rok vydání: | 2015 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Cost-Benefit Analysis Reminder Systems MEDLINE Anti-asthmatic Agent law.invention Medication Adherence 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Quality of life law immune system diseases Adrenal Cortex Hormones Health care Administration Inhalation Outpatients medicine Outpatient clinic Humans 030212 general & internal medicine Anti-Asthmatic Agents Child Asthma Text Messaging Inhalation business.industry Health Care Costs medicine.disease respiratory tract diseases 030228 respiratory system Child Preschool Physical therapy Disease Progression Quality of Life Female Drug Monitoring business |
| Zdroj: | European respiratory journal, 48(3), 758-767. European Respiratory Society |
| ISSN: | 1399-3003 0903-1936 |
| Popis: | Real-time medication monitoring (RTMM) is a promising tool for improving adherence to inhaled corticosteroids (ICS), but has not been sufficiently tested in children with asthma. We aimed to study the effects of RTMM with short message service (SMS) reminders on adherence to ICS, asthma control, asthma-specific quality of life and asthma exacerbation rate; and to study the associated cost-effectiveness.In a multicentre, randomised controlled trial, children (aged 4–11 years) using ICS were recruited from five outpatient clinics and were given an RTMM device for 12 months. The intervention group also received tailored SMS reminders, sent only when a dose was at risk of omission. Outcome measures were adherence to ICS (RTMM data), asthma control (childhood asthma control test questionnaire), quality of life (paediatric asthma quality of life questionnaire) and asthma exacerbations. Costs were calculated from a healthcare and societal perspective.We included 209 children. Mean adherence was higher in the intervention group: 69.3%versus57.3% (difference 12.0%, 95% CI 6.7%–17.7%). No differences were found for asthma control, quality of life or asthma exacerbations. Costs were higher in the intervention group, but this difference was not statistically significant.RTMM with tailored SMS reminders improved adherence to ICS, but not asthma control, quality of life or exacerbations in children using ICS for asthma. |
| Databáze: | OpenAIRE |
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