Stereoselective traceless borylation–allenation of propargylic epoxides: dual role of the copper catalyst
| Autor: | Mariola Tortosa, Carlos Jarava-Barrera, Alejandro Parra, Ana Arroyo, Laura Amenós |
|---|---|
| Přispěvatelé: | UAM. Departamento de Química Orgánica |
| Rok vydání: | 2017 |
| Předmět: |
010405 organic chemistry
Organic Chemistry chemistry.chemical_element General Chemistry Química 010402 general chemistry 01 natural sciences Borylation Copper Catalysis 0104 chemical sciences Hydroboration epoxides Dual role chemistry allenes copper Organic chemistry Stereoselectivity Boron boron stereoselective synthesis Stoichiometry |
| Zdroj: | Biblos-e Archivo: Repositorio Institucional de la UAM Universidad Autónoma de Madrid Biblos-e Archivo. Repositorio Institucional de la UAM instname |
| Popis: | This is the peer reviewed version of the following article: Chemistry: A European Journal 23.69 (2017): 17478 –17481, which has been published in final form at http://doi.org/10.1002/chem.201705019. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving Chiral α-allenols are prepared with high diastereocontrol through an unprecedented and spontaneous β-oxygen elimination of an α-epoxy vinyl boronate. Stochiometric experiments and DFT calculations support a dual role of the copper catalyst, which orchestrates the hydroboration and the syn-elimination step The European ResearchCouncil (ERC-337776) and MINECO (CTQ2016-78779-R) for financial support M.T.thanks MICINNfor a RyC contract |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|