Relations between hepatobiliary scintigraphy findings and histopathological factors in patients with recurrent biliary colic
| Autor: | Hyun Ju Lee, Jeong Won Lee, Mee-Hye Oh, Hae Il Jung, Hyein Ahn, Ji-Hye Lee, Si-Hyong Jang, Sang Mi Lee |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Colic medicine.medical_treatment Gallbladder Diseases Biliary colic Scintigraphy Gastroenterology 030218 nuclear medicine & medical imaging Muscle hypertrophy 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Radionuclide Imaging Retrospective Studies Ejection fraction Hepatology medicine.diagnostic_test business.industry Gallbladder medicine.disease Empyema medicine.anatomical_structure Cholecystitis 030211 gastroenterology & hepatology Surgery Cholecystectomy medicine.symptom business |
| Zdroj: | Journal of Hepato-Biliary-Pancreatic Sciences. 27:839-850 |
| ISSN: | 1868-6982 1868-6974 |
| Popis: | Background/purpose The aim of the present study was to investigate the relationship between hepatobiliary scintigraphy findings and histopathological results in patients with recurrent biliary colic. Methods We retrospectively enrolled 107 patients who underwent hepatobiliary scintigraphy for recurrent biliary colic and subsequent cholecystectomy. According to the hepatobiliary scintigraphy findings, patients were categorized into a nonvisualization of gallbladder activity (nonvisualized GB) group, low gallbladder ejection fraction (GBEF) group, and normal GBEF group. Differences in histopathologic factors between the three groups were evaluated and multivariate logistic regression analyses were performed to identify histopathological predictors for hepatobiliary scintigraphy findings. Results The nonvisualized group had a higher frequency of patients with empyema and severe infiltration by neutrophils, lymphoplasma cells, and eosinophils. The low GBEF group had a higher muscle-to-total wall thickness ratio and muscle-to-fibrosis thickness ratio of the gallbladder wall than those in the normal GBEF group. On multivariate logistic regression analyses, severe degrees of lymphoplasma cell infiltration and eosinophil infiltration were independent predictors for nonvisualization of gallbladder activity, and a higher muscle-to-fibrosis thickness ratio was an independent predictor for low GBEF. Conclusions In patients with recurrent biliary colic, nonvisualization of gallbladder activity on hepatobiliary scintigraphy was related to the degree of inflammation in the gallbladder, while low GBEF was related to muscular hypertrophy of the gallbladder. |
| Databáze: | OpenAIRE |
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