Evaluation of Nasal Mucociliary Clearance Time in COVID-19 Patients
| Autor: | Özgür Günal, Gokhan Giray Akgul, Cem Bayraktar, Ayşe Çeçen, Abdulkadir Özgür |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Mucociliary clearance smokers Nose 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Humans Medicine Patient group 030223 otorhinolaryngology Saccharin Coronavirus disease 2019 mucociliary clearance time Adult patients SARS-CoV-2 business.industry Smoking Significant difference COVID-19 030206 dentistry General Medicine Brief Clinical Studies Smoking control Nasal Mucosa Otorhinolaryngology chemistry Mucociliary Clearance Surgery viral infection business |
| Zdroj: | The Journal of Craniofacial Surgery |
| ISSN: | 1536-3732 1049-2275 |
| Popis: | BACKGROUND: Coronavirus Disease 2019 (COVID-19) is a viral pandemic emerging in East Asia and spreading rapidly to the rest of the world and continuing in our country. The number of studies examining the symptoms of the otolaryngology system and organs in COVID-19 patients is limited. The purpose of this study is to show whether COVID-19 infections cause any changes in nasal physiology in adult patients by measuring the mucociliary clearance (MCC) time with the saccharin test. METHODS: One hundred one patients with laboratory-confirmed COVID-19 infection (group 1, nâ=â42 smokers and group 2, nâ=â59 nonsmokers) and 87 individuals without COVID-19 infection as the control group (group 3, nâ=â33 smokers and group 4, nâ=â54 nonsmokers) were included in the study. A saccharin test was used to evaluate the nasal MCC time. RESULTS: Mucociliary clearance test averages of the groups were determined as 473.571â±â263.684, 442.966â±â228.463, 468.333â±â267.367, 412.629â±â192.179 seconds, respectively. When the test durations were examined, the group with the most prolonged MCC duration was determined as the smoking COVID (+) patient group (473.571â±â263.684âseconds). The second group, with the most prolonged MCC duration, was determined as the smoking control group (468.333â±â267.367âseconds). No statistically significant difference was found in intergroup mucociliary clearance time (Pâ=â0.760). CONCLUSION: Although the authors found that smoking and viral infections prolong the MCC duration in our study, they did not find a statistically significant difference between the groups in terms of MCC duration. |
| Databáze: | OpenAIRE |
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