The Patient Care Monitor-Neutropenia Index: development, reliability, and validity of a measure for chemotherapy-induced neutropenia
| Autor: | Arthur C. Houts, Scott A. Baldwin, James P. Olsen |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Neutropenia Psychometrics medicine.medical_treatment Antineoplastic Agents Patient care Chemotherapy induced hemic and lymphatic diseases Internal medicine Neoplasms medicine Humans In patient skin and connective tissue diseases Reliability (statistics) Aged Aged 80 and over Chemotherapy Receiver operating characteristic business.industry Oncology Nursing Reproducibility of Results Middle Aged medicine.disease ROC Curve Quality of Life Female Drug Monitoring business Febrile neutropenia |
| Zdroj: | Oncology nursing forum. 38(3) |
| ISSN: | 1538-0688 |
| Popis: | PURPOSE/OBJECTIVES To provide an initial evaluation of the psychometric properties of the Patient Care Monitor 1.0 Revised-Neutropenia Index (PCM-N), a symptom-based assessment tool designed to measure health-related quality-of-life (HRQOL) changes associated with chemotherapy-induced neutropenia. DESIGN Known-groups methodology and self-report instrument validation. SETTING A large community oncology practice in Memphis, TN. SAMPLE 424 patients with cancer in four samples. METHODS All patients in the first three samples were assessed at baseline of chemotherapy administration and at a point analogous to midcycle. The fourth sample underwent a cross-sectional evaluation of the ability of the PCM-N to distinguish patients with febrile neutropenia, severe afebrile neutropenia, and no neutropenia. MAIN RESEARCH VARIABLES PCM-N score, grade of neutropenia, and febrile status. FINDINGS Internal consistency reliability and factor analysis supported the single additive scale structure of the 13 items of the PCM-N. The PCM-N demonstrated good known-groups validity and was able to distinguish patients with grades 3-4 neutropenia from those with grades 0-2. The tool also was able to distinguish patients with febrile neutropenia, severe afebrile neutropenia, and no neutropenia. Receiver operating characteristic analyses provided a psychometrically based threshold score. CONCLUSIONS The PCM-N is a reliable and valid instrument sensitive to changes in HRQOL associated with moderate-to-severe chemotherapy-induced neutropenia. IMPLICATIONS FOR NURSING Nurses can use the PCM-N as a rapid and cost-effective tool for monitoring symptoms of neutropenia in patients with cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|