Nanoscale PDA disassembly in ionic liquids: structure-property relationships underpinning redox tuning
| Autor: | Andrea Mezzetta, Marianna Ambrico, Cinzia Chiappe, Paola Franchi, G. Casamassima, Paolo F. Ambrico, Luca Valgimigli, Marco d'Ischia, Paola Manini, Teresa Ligonzo |
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| Přispěvatelé: | Ambrico, M., Manini, P., Ambrico, P. F., Ligonzo, T., Casamassima, G., Franchi, P., Valgimigli, L., Mezzetta, A., Chiappe, C., D'Ischia, M., Ambrico M., Manini P., Ambrico P.F., Ligonzo T., Casamassima G., Franchi P., Valgimigli L., Mezzetta A., Chiappe C., D'Ischia M. |
| Rok vydání: | 2019 |
| Předmět: |
polydopamine (PDA)
DRUG DELIVERY Materials science General Physics and Astronomy Nanoparticle Nanotechnology electrical impedance spectroscopy (EIS) 02 engineering and technology Polidopamine 010402 general chemistry 01 natural sciences Redox law.invention Ion SURFACE-CHEMISTRY chemistry.chemical_compound law Electrical impedance spectroscopy POLYDOPAMINE NANOPARTICLES SURFACE-CHEMISTRY DRUG DELIVERY POLYMER DRUG-DELIVERY Physical and Theoretical Chemistry Electron paramagnetic resonance Nanoscopic scale ionic liquid REDOX Rational design POLYMER Nanoscale disassembly 021001 nanoscience & nanotechnology 0104 chemical sciences electron paramagnetic resonance (EPR) chemistry Ionic liquid Drug delivery POLYDOPAMINE NANOPARTICLES 0210 nano-technology |
| Zdroj: | PCCP. Physical chemistry chemical physics 21 (2019): 12380–12388. doi:10.1039/c9cp01545k info:cnr-pdr/source/autori:Ambrico, Marianna; Manini, Paola; Ambrico, Paolo F.; Ligonzo, Teresa; Casamassima, Giuseppe; Franchi, Paola; Valgimigli, Luca; Mezzetta, Andrea; Chiappe, Cinzia; d'Ischia, Marco/titolo:Nanoscale PDA disassembly in ionic liquids: structure-property relationships underpinning redox tuning/doi:10.1039%2Fc9cp01545k/rivista:PCCP. Physical chemistry chemical physics (Print)/anno:2019/pagina_da:12380/pagina_a:12388/intervallo_pagine:12380–12388/volume:21 |
| ISSN: | 1463-9084 |
| DOI: | 10.1039/c9cp01545k |
| Popis: | Nanoscale disassembly of mussel-inspired polydopamine (PDA) in ionic liquids (ILs) was recently shown to induce an electron paramagnetic resonance (EPR)-detectable reorganization of free radical centers in the resulting nanoparticles (NPs) in an IL-controlled manner. Herein, we report electrical impedance spectroscopy (EIS) data showing that PDA NPs produced by suspending samples obtained in Tris and bicarbonate buffer (PDA-T and PDA-C) in different ILs display different redox activity as a result of structural control combined with IL-surface interactions. In particular, susceptibility to oxidation was found to correlate closely with the spin density in an ion pair-tunable fashion in ILs. Structural control over free radical properties and redox behavior of PDA NPs in ILs opens novel perspectives for the rational design of functional nanovectors of possible interest for drug delivery and theranostic applications. |
| Databáze: | OpenAIRE |
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