Imaging Pulmonary Inflammation
| Autor: | Philip M. Scherer, Delphine L. Chen |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Inflammation
Bioinformatics Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Immune system medicine Humans Radiology Nuclear Medicine and imaging Lung Lung function business.industry Pulmonary inflammation Respiratory disease Reproducibility of Results Pneumonia respiratory system medicine.disease Image Enhancement respiratory tract diseases Continuing Education medicine.anatomical_structure 030228 respiratory system Positron-Emission Tomography medicine.symptom Molecular imaging business |
| Zdroj: | Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 57(11) |
| ISSN: | 1535-5667 |
| Popis: | Lung inflammatory diseases contribute significantly to the socioeconomic burden of disease. Yet very few new, effective therapies for respiratory disease have been approved for use. A major contributing factor is the lack of biomarkers that can accurately quantify the lung inflammatory burden and can be used to understand the contribution of lung inflammation to loss in lung function. Molecular imaging approaches can detect and quantify the recruitment and activation of specific immune cells in lung inflammation. We review the clinical techniques used to image lung inflammation, provide an overview of clinical and emerging PET techniques for quantifying lung inflammation, and discuss potential clinical applications. |
| Databáze: | OpenAIRE |
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