Is abnormal non-high-density lipoprotein cholesterol a gender-specific predictor for metabolic syndrome in patients with schizophrenia taking second-generation antipsychotics?

Autor: Miaofen Yen, Wen Chuan Shao, Ru Band Lu, Sheng-Yu Lee, Hsin Ju Yang, Esther Ching-lan Lin, Pei Chun Wu
Rok vydání: 2014
Předmět:
Zdroj: Metabolic Brain Disease. 30:107-113
ISSN: 1573-7365
0885-7490
Popis: Evidence supports an association between metabolic syndrome (MetS) and schizophrenia. However, specific risk factors for MetS and gender differences in patients with schizophrenia taking second-generation antipsychotics (SGAs) have not been well explored. A cross-sectional cohort of 329 Han Chinese patients was recruited in a psychiatric hospital in central Taiwan. Using the definitions of the International Diabetes Federation for Chinese, the prevalence of MetS was 23.7 % (men: 25.7 %; women: 21.2 %). Logistic regression analyses showed that patients with a BMI ≥ 24 and an abnormal non-high-density lipoprotein cholesterol (non-HDL-C) were significantly (p
Databáze: OpenAIRE