Progestins for contraception: modern delivery systems and novel formulations
| Autor: | Pamela A. Royer, Kirtly Parker Jones |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
animal structures
medicine.drug_class Transdermal Patch Medroxyprogesterone Acetate Pharmacology Contraceptives Oral Hormonal polycyclic compounds medicine Contraceptive Agents Female Humans reproductive and urinary physiology Drug Implants Progesterone Congeners urogenital system Contraceptive Devices business.industry Combined oral contraceptives Intrauterine Devices Medicated Obstetrics and Gynecology Contraceptive Devices Female Estrogens Venous Thromboembolism Contraceptives Oral Combined Family planning Female Progestins business Progestin hormones hormone substitutes and hormone antagonists |
| Zdroj: | Clinical obstetrics and gynecology. 57(4) |
| ISSN: | 1532-5520 |
| Popis: | Since the development of combined oral contraceptives over 50 years ago, significant innovations have occurred in the domain of the progestin. Evolving knowledge of progestin mechanism of action and physiology has allowed for development of novel progestins with limited steroid receptor cross-reactivity, decreased side effect profiles, and pharmacokinetics optimized for modern delivery systems. This review summarizes current knowledge of progestin physiology, modern delivery systems, and developments of progestin agonists and antagonists for contraception. |
| Databáze: | OpenAIRE |
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