Mixed meningeal and brain plasma-cell granuloma: an example of an unusual evolution
| Autor: | William Pellet, P.-H. Roche, Dominique Figarella-Branger |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Pathology medicine.medical_specialty medicine.medical_treatment Granuloma Plasma Cell Lesion Meninges Seizures Biopsy Parenchyma medicine Humans Neuroradiology Brain Diseases medicine.diagnostic_test business.industry Magnetic resonance imaging medicine.disease Plasma cell granuloma Radiation therapy Treatment Outcome Granuloma Female Steroids Surgery Neurology (clinical) medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Acta Neurochirurgica. 146:69-72 |
| ISSN: | 0942-0940 0001-6268 |
| DOI: | 10.1007/s00701-003-0153-8 |
| Popis: | We report a study of a 22-year-old woman with a plasma-cell granuloma (PCG), a rare intracranial lesion characterized by a non-neoplastic polyclonal proliferation of plasma cells and other mononuclear cells. She presented after a generalized seizure and CT-scan and magnetic resonance images demonstrated a left temporo-basal tumour mass involving both the meningeal layers and the brain parenchyma. Histopathological examination of a biopsy led to the diagnosis of a typical PCG. After a short course of steroid administration, the clinical and radiological features improved and complete regression of the lesion was shown after one year and persisted at four-year follow-up. This dramatic regression of an intracranial PCG shows that neither surgical removal nor radiation therapy is required to treat a broad skull base PCG. |
| Databáze: | OpenAIRE |
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